Rady Children's Hospital - Orange County

Children's Hospital of Orange County

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Children's Hospital of Orange County is now part of Rady Children's Health. Learn More

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Leading research. Lasting impact.

CHOC, part of Rady Children's Health, offers access to cutting-edge pediatric research and clinical trials that can’t be found anywhere else.

Clinical Trials Latest Research
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Home » Research Institute

CHOC Research Institute

  • Research Institute Home
    • About the Research Institute
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    • Latest Research
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      • Located in the CHOC Research Building – 4th Floor
      • Phone (714) 509-4341
      • Fax: (714) 509-4318
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    • Areas of Focus
      • Autism and Neurodevelopmental Disorders Research
      • Cancer Research and Clinical Trials
      • Computational and Data Science Research
      • Infectious Disease Research
      • Metabolic Rare Disease Research
      • Neonatal Research
      • Neuroscience Research
      • Nursing Research and Evidence-Based Practice (EBP)
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PEDIATRIC & LIFESPAN DATA SCIENCE CONFERENCE 2026

Wednesday, April 29 — Thursday, April 30th


COMING SOON

See Event Details

At CHOC, now part of Rady Children’s Health, we know research not only saves lives — it gives future generations the chance to live to their fullest potential. Guided by our commitment to “go beyond”, our team asks the difficult questions, solves complex problems, and forges new approaches to treatment that benefit patients now and in the future. Through our Research Institute in Orange County, we have more than 600 studies in over 30 specialties, giving children access to some of the most advanced treatments available. Our scientists apply the latest advances in molecular profiling, including whole genome sequencing, to deliver care tailored to each child’s needs — from infancy through adolescence.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute is part of Rady Children’s Health and supports more than 600 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

View Clinical Trials
“We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.”
Dr Terence Sanger

Terence Sanger

Chief Scientific Officer at CHOC, part of Rady Children’s Health

Latest Research

  • Multimodal Noninvasive Biomarker Characterization of Structural and Functional Alterations in ADSS1-Deficient Myopathy
    by Merve Koç Yekedüz
  • Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states
    by Ester Calvo Fernández
  • Optimizing human milk provision: Review of QI best practices
    by Anthony J Piazza
  • Relationships between cerebral blood flow and cognition in young adults born very preterm and at term
    by Chandelle L Piazza
  • Temporoparietal Fascial Free Flap With Vascularized Helical Rim Component for Complex Nasal Reconstruction
    by Asha D Nanda
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Research Stories

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Artificial Intelligence

Pediatric & Lifespan Data Science Conference 2026 to address the challenges of AI in translational research while driving real-world social impact

The program will feature several keynote addresses, panels exploring the role of AI and AI agents, a hackathon focused on developing cutting-edge applications to address…

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Healthcare

From unanswered questions to transformative care: 2026 Rare Disease Symposium and Family Conference

The gathering brings together clinicians, researchers, patients, families, and industry partners — fostering awareness, equity, and progress in rare disease diagnosis and treatment.

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Banner showing OC Impact Conference

Healthcare

CHOC, University Lab Partners, UC Irvine host industry leaders at healthcare forum

Experts discuss enhancing the research and development (R&D) pathway and improving patient outcomes.

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Rady Children's Hospital - Orange County

Rady Children's Health: formerly Children's Hospital of Orange County

1201 W La Veta Ave
Orange, CA 92868

(714) 997-3000

Rady Children's Health in Orange County is affiliated with

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