Questions about your child's health? Call our free 24/7 Nurse Advice Line 844-GET-CHOC.

Free 24/7 Nurse Advice Line: 844-GET-CHOC.

Home » CHOC Research Institute

CHOC Research Institute

Terence Sanger, Chief Scientific Officer at CHOC, speaks to the importance of research at a children’s hospital.

We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.

At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute supports more than 350 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Latest Research

Safety, Tolerability, and Pharmacokinetics of Long-Acting Broadly Neutralizing HIV-1 Monoclonal Antibody VRC07523LS in Newborn Infants Exposed to HIV-1

Exploring treatment-driven subclonal evolution of prognostic triple biomarkers: Dual gene fusions and chimeric RNA variants in novel subtypes of acute myeloid leukemia patients with KMT2A rearrangement

Depression in children with abdominal pain in the emergency department

Trochleoplasty Utilization in the Management of Patellofemoral Instability: Results From an International Survey of Surgeons

Assessing Clinical Improvement of Infants Hospitalized for Respiratory Syncytial Virus-Related Critical Illness

Mitigating the Risk of QTc Prolongation When Using Haloperidol for Acute Treatment of Cannabinoid Hyperemesis Syndrome in Adolescents and Young Adults

Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors

Research Professionals

The Research Institute is committed to delivering comprehensive service, from pre-award assistance to post-award management. We make every effort to accommodate individual researcher's needs and schedules within the resources of our office, and we act as an advocate for the faculty and the university in the research process.

Institutional Review Boards

Institutional Review Boards
CHOC currently has two Institutional Review Boards

Research Administration

Research Administration
CHOC's Research Administration office is a valuable resource for the CHOC community, providing expertise and highly specialized service in the important area of research management.