Rady Children's Hospital - Orange County

Children's Hospital of Orange County

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Children's Hospital of Orange County is now part of Rady Children's Health. Learn More

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Leading research. Lasting impact.

CHOC, part of Rady Children's Health, offers access to cutting-edge pediatric research and clinical trials that can’t be found anywhere else.

Clinical Trials Latest Research
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Home » Research Institute

CHOC Research Institute

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      • Located in the CHOC Research Building – 4th Floor
      • Phone (714) 509-4341
      • Fax: (714) 509-4318
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    • Areas of Focus
      • Autism and Neurodevelopmental Disorders Research
      • Cancer Research and Clinical Trials
      • Computational and Data Science Research
      • Infectious Diseases Research
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At CHOC, now part of Rady Children’s Health, we know research not only saves lives — it gives future generations the chance to live to their fullest potential. Guided by our commitment to “go beyond”, our team asks the difficult questions, solves complex problems, and forges new approaches to treatment that benefit patients now and in the future. Through our Research Institute in Orange County, we have more than 600 studies in over 30 specialties, giving children access to some of the most advanced treatments available. Our scientists apply the latest advances in molecular profiling, including whole genome sequencing, to deliver care tailored to each child’s needs — from infancy through adolescence.

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute is part of Rady Children’s Health and supports more than 600 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

View Clinical Trials
“We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.”
Dr Terence Sanger

Terence Sanger

Chief Scientific Officer at CHOC, part of Rady Children’s Health

Latest Research

  • Clinical trial barriers in neurostimulation for pediatric drug-resistant epilepsy
    by Mira C Hasner
  • Operative Timing of Resection in Prenatally Diagnosed Congenital Lung Malformations Among Major Children's Hospitals in the United States
    by Kyra M Halbert-Elliott
  • Associations Between Paternal Sensitivity and Cognitive and Behavioural Outcomes in Preterm Children: An Individual Participant Data Meta-Analysis
    by Noa Gueron-Sela
  • Update on Approved Therapies for Dystrophic and Junctional Epidermolysis Bullosa
    by Alberto Pappalardo
  • Timing of Inguinal Hernia Repair Does Not Influence Recurrence in Premature Infants
    by Stephanie F Brierley
Person in white coat with gloved hand conducting research.

Research Stories

Heart and doctor

Healthcare

Study supports tailored temperature management for preventing neurological injuries in congenital heart surgery

A Rady Children’s Health Orange County study found that tailoring temperature management during congenital heart surgery may improve neurological outcomes.

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Cancer cells

Cancer / Oncology

Envisioning the future of precision oncology by reframing cancer relapse

The recent discovery of a previously unknown fusion gene in acute myeloid leukemia (AML) is shifting current thinking about cancer’s dynamic nature and the drivers…

CHOC Logo Icon CHOC Pediatrica

Young boy taking out toys from a plastic container, visibly upset and bored, sitting on the floor in his room with scattered toys and a bed nearby

Research

The Orange County Register: New study: Unpredictability in childhood linked to depression, obesity and mental health risks later

New research from UC Irvine, Chapman and Rady Children’s finds unpredictable childhood home environments may increase risks of depression, obesity and mental health issues.

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Rady Children's Hospital - Orange County

Rady Children's Health: formerly Children's Hospital of Orange County

1201 W La Veta Ave
Orange, CA 92868

(714) 997-3000

Rady Children's Health in Orange County is affiliated with

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