Protecting childhood through leading neurological care.
Our Neuroscience Institute combines specialized skills with the latest technology to treat an array of pediatric brain conditions.

Neuroscience Institute
Call today to schedule an appointment with one of our pediatric specialists.
Neurology Referrals
View the referral guidelines
Neurosurgery Referrals
As a parent, you are the ultimate protector of your child, and you want the best possible medical care when your child has been diagnosed with a neurological condition. We know that managing your child’s condition can be overwhelming and you might not know where to start.
The CHOC Neuroscience Institute is a dedicated place for kids. Our team of board-certified specialists and neuroscience-trained staff provide a full spectrum of care for disorders of the brain, spine, muscles and central and peripheral nervous systems. We provide coordinated care for a seamless experience, innovative programs and specialized treatments, and pediatric expertise, equipment and facilities.
Brain conditions in children can be complex and require a team of caregivers, each bringing special expertise. Your child’s care team may include board-certified neurologists and neurosurgeons, nurses and nurse practitioners, social workers, neuropsychologists, rehabilitation therapists, dietitians, psychiatrists, pharmacists, speech and occupational therapists, and child life specialists.





The CHOC Difference
- We offer the only pediatric neuroscience inpatient unit in the region, designed with private, spacious rooms, advanced continuous monitoring.
- Our innovative playroom is equipped with AirEEG technology and allows our patients to play while staying connected wirelessly to the EEG monitoring system. Specialized play programming is also provided to support neurodiverse patients.
- We have the only Level 4 epilepsy center in Orange County, certified by the National Association of Epilepsy Centers (NAEC).
- Our operating rooms feature top navigation systems including FIREFLY and StealthStation S8 with 3D visualization, allowing surgeons to perform safer, more precise procedures.
- Minimally invasive surgery tools including MRI-guided laser ablation and ROSA, a 3D-mapping robotic system that aids surgeons in locating the exact area to operate.
- Video EEG monitoring is wired throughout our hospital, and at-home units allow children to play and move about normally while undergoing detailed monitoring of the brain
- ReFlow shunt technology reverses life-threatening shunt occlusion in patients with hydrocephalus.
- We offer vagus nerve stimulation (VNS), a “pacemaker for the brain” for reducing seizures, and deep brain stimulation (DBS) for intractable partial seizures and dystonia.
- Muscular dystrophy and muscle diseases
- Neural tube defects (spina bifida, encephalocele, anencephaly)
- Neurofibromatosis
- Sleep disorders
- Spasticity
- Spina bifida
- Spinal dysraphism
- Stroke
- Tics and Tourette syndrome
- Traumatic brain injuries (TBI) and other head injuries
- Epilepsy
- Cerebral Palsy and Spasticity
- Hydrocephalus
- Tumors of the Brain and Spine
- Brachial Plexus Nerve Damage
- Moyamoya Disease
- Craniosynostosis
- Birth Defects
- Brain Cysts
- Concussion and Head/Spinal Cord Trauma

Stories from the Neuroscience Institute
Cancer / Oncology
Patient’s journey illustrates strength of neuro-oncology programs at CHOC, Rady Children’s
Trent Cirigliano, 13, spent two years at CHOC and Rady Children’s for treatment of a brain tumor that included proton therapy and a clinical trial.
CHOC Health
Health
Easton’s cranioversary: Strength beyond the scar
At five months old, Easton had cranial vault remodeling to correct skull shape abnormalities. Now, he celebrates his ‘cranioversary’ or ‘scar day’ each year.
CHOC Health
Epilepsy / Seizures
CHOC epilepsy patient sees longtime success through vagus nerve stimulator device
Porsche’s outcome is just one example of patient successes celebrated at CHOC’s first annual epilepsy surgery patient reunion.
CHOC Health
Healthcare
Down syndrome study at CHOC is part of a new multicenter research award from the NIH
The project aims to bring new insight into how metabolic health, obesity, sleep apnea and lifestyle contribute to cognitive impairments, Alzheimer’s disease and other conditions…
CHOC Pediatrica
Healthcare
Department of Defense grant boosts CHOC’s research into novel hydrocephalus treatment
CHOC Neuroscience Institute to study a non-surgical way to treat the debilitating and complex disease.
CHOC Pediatrica
Epilepsy / Seizures
Searching for a cure at CHOC’s Rett Syndrome Center of Excellence
Learn about the Rett Syndrome Center of Excellence at CHOC and how upcoming clinical trials hold hope for a cure and better treatment.
CHOC Pediatrica
Outpatient Locations
Call us today at 714-509-4765 for appointments with a neurologist or neurosurgeon, scheduling a neurodiagnostic test, physician referrals and general questions about our programs and services.