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Children's Hospital of Orange County

Children's Hospital of Orange County

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Questions about your child's health? Call our free 24/7 Nurse Advice Line 844-GET-CHOC.

Leading-edge Children’s Research

CHOC offers access to cutting-edge pediatric research and clinical trials that can’t be found anywhere else.

Clinical Trials Latest Research
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Home » Research Institute

CHOC Research Institute

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      • Located in the CHOC Research Building – 4th Floor
      • Phone (714) 509-4341
      • Fax: (714) 509-4318
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    • Areas of Focus
      • Autism and Neurodevelopmental Disorders Research
      • Cancer Research and Clinical Trials
      • Computational and Data Science Research
      • Infectious Disease Research
      • Metabolic Rare Disease Research
      • Neonatal Research
      • Neuroscience Research
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Research Newsletter

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At CHOC, we know that research saves lives. That’s why our Research Institute has more than 500 research studies in more than 30 specialties to provide your child with access to leading-edge treatments. Our scientists translate the latest advances in molecular profiling, including whole genome sequencing, to meet the individual needs of our patients at every stage of their young lives —from infancy through adolescence.

“We conduct research directly with children and adolescents in a facility devoted exclusively to the care, quality of life, rights and safety of children of all ages.”
Dr Terence Sanger

Terence Sanger

Chief Scientific Officer at CHOC

Research Areas of Focus:

  • Autism & Neurodevelopmental Disorders Research
  • Cancer Research
  • Genetic & Molecular Research
  • Infectious Disease Research
  • Metabolic Rare Disease Research
  • Neonatal Research
  • Neuroscience Research
  • Nursing Research
  • Orthopaedic Research
  • Population Health Research
  • Research Computational Science
  • Stem Cell Research

About the CHOC Research Institute

The CHOC Research Institute was formally established in 2003, after years of active participation in pediatric clinical research. Today, the Research Institute supports more than 350 active human-subject research studies across nearly all of our pediatric subspecialty areas.

The Institute’s Sponsored Projects and Research Compliance offices administer and oversee federal NIH, California State CIRM, private foundation and donor funding in support of translational and clinical child health research.

The Research Institute also has a formal affiliation with UC Irvine, a collaboration that brings advanced treatment to patients. Through the partnership, additional grants have been awarded to both institutions, and CHOC researchers have access to valuable University resources, like the Beckman Laser Institute, in an effort to bring breakthrough therapies and cures to pediatric patients.

Clinical Trials

At CHOC, we are dedicated to providing patients the very latest breakthrough treatments available to children, adolescents and young adults. Our efforts bring hope to patients with rare conditions, or conditions not responding to traditional treatments.

View Clinical Trials

Latest Research

  • ESPGHAN/NASPGHAN guidelines for treatment of irritable bowel syndrome and functional abdominal pain-not otherwise specified in children aged 4-18 years
    by Jip Groen
  • Optimizing Voriconazole Dosing in Extremely Premature Infants With Aspergillus Infections
    by Adam Lee
  • Characterizing the preserved ratio impaired spirometry phenotype in all severities of asthma
    by Marcello Cottini
  • Patellar Instability Events Requiring Emergency Department Management – A 20-year Analysis
    by David Kell
  • State of the art management practices for liver glycogen storage disorders: Results from an international survey among metabolic centres
    by Sarah C Grünert
Person in white coat with gloved hand conducting research.

Research Stories

Child uses iPad in class - What parents should know about AI

Artificial Intelligence

Artificial Intelligence (AI) and kids: What parents should know

A CHOC expert explains the benefits of AI in pediatric healthcare and how it may affect the health of kids and teens.

CHOC Logo Icon CHOC Health

Child holds autism awareness puzzle pieces

Autism

Enjoy the journey: Advice from one autism parent to another

A proud CHOC mom offers lessons learned from her family’s over 20 years of experience with autism spectrum disorder.

CHOC Logo Icon CHOC Health

Child on mechanical bull. Mechanical bulls may be dangerous for kids.

Neurology

Mechanical bull riding may cause severe injuries in kids

A CHOC research study discovers the injury risks and safety of mechanical bull riding for kids and encourages more safety precautions.

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Conference flyer on table

Artificial Intelligence

Experts address the most pressing challenges at Pediatric & Lifespan Data Science Conference

Panel discussions also were held on precision medicine, fairness in AI, precision management of psychiatric conditions, and other issues.

CHOC Logo Icon CHOC Pediatrica

Cardiac MRI

Healthcare

CHOC-led study explores cardiac MRI for borderline left ventricle surgery

The new study is an example of how CHOC and UCLA Health are transforming the way cardiac care is being delivered in Southern California.

CHOC Logo Icon CHOC Pediatrica

child with down syndrome holding his hands up

Healthcare

Down syndrome study at CHOC is part of a new multicenter research award from the NIH

The project aims to bring new insight into how metabolic health, obesity, sleep apnea and lifestyle contribute to cognitive impairments, Alzheimer’s disease and other conditions…

CHOC Logo Icon CHOC Pediatrica

1201 W La Veta Ave
Orange, CA 92868

(714) 997-3000

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