Dr. Shawn Sen, Neonatology

Dr. Shawn Sen, MD, is a dual board-certified physician in neonatology and pediatric cardiology and serves as director of the Cardiovascular NICU (CVNICU) at Rady Children’s Hospital-Orange County. He practices as a neonatal cardiac intensivist, specializing in the care of critically ill neonates with infants with complex congenital heart disease.

Dr. Sen is nationally recognized for advancing multidisciplinary care models for neonatal cardiovascular care, with a clinical and research focus on optimizing outcomes for infants with severe cardiac conditions. His work bridges the fields of neonatology and cardiology to deliver developmentally informed, evidence-based care across the continuum from birth through early childhood.

He earned his medical degree from the University of Oklahoma College of Medicine and completed his pediatric residency at Columbia University’s Morgan Stanley Children’s Hospital. He subsequently completed two pediatric subspecialty fellowships: Neonatology at UT Southwestern Medical Center and Pediatric Cardiology at Stanford University’s Lucile Packard Children’s Hospital.

In his current role, Dr. Sen plays an integral role in the CHOC-UCLA Mattel Children’s Hospital Congenital Heart Program and leads multiple innovative initiatives aimed at optimizing outcomes for infants with severe cardiac conditions, including the development of the Infant Cardiac Critical Care (IC3) Program at CHOC. Additionally, he serves as the faculty lead for the Cardiac High-Risk Interstage Program (CHIP) and the cardiac inpatient developmental team. His efforts focus on implementing developmentally informed, evidence-based protocols for inpatient care, bridging neonatology and cardiology to provide comprehensive, long-term support for vulnerable patients and their families.

Locations

CHOC Specialists, Neonatology
1201 W. La Veta Ave.
Orange, CA 92868
phone: 714-509-4373
fax: 714-509-7800

Education

• Medical School
  University of Oklahoma – Oklahoma City, OK
• Residency
  Columbia University Medical Center, New York, NY
• Neonatology Fellowship
  University of Texas Southwestern Medical Center, Dallas, TX
• Pediatric Cardiology Fellowship
  Stanford University, Lucile Packard Children’s Hospital, Palo Alto, CA

Administrative Appointments

• CV NICU Director, Neonatology, CHOC Specialists
• Pediatric Cardiology, CHOC Specialists

Academic Appointments

• Associate Professor of Pediatrics, University of California Irvine School of Medicine

Publications

Pardo AC, Carrasco M, Chock VY, Sen S, et al. Neuromonitoring practices for neonates with congenital heart disease: a scoping review. Pediatr Res. 2025 Apr;97(5):1492-1506.

Chaudhry PM, Sen S, et al. Perioperative Care Models for Neonates with Congenital Heart Disease: Evolving Role of Neonatology Within the Cardiac Intensive Care Unit. World J Pediatr Congenit Heart Surg. 2023;21501351231170772.

Patel SG, Koenig P, Myers P, Sen S. Development of a neonatal cardiac curriculum for neonatal-perinatal medicine fellowship training. J Perinatol. 2024; 44(8):1186-1192.

Cooper DS, Hill KD, Krishnamurthy G, Sen S, et al. Acute Cardiac Care for Neonatal Heart Disease. Pediatrics. 2022;150 (Suppl 2):e2022056415J.

Dudley S, Sen S, Hanson A, El Khuffash A, Levy PT. The role of furosemide and fluid management for a hemodynamically significant patent ductus arteriosus in premature infants. J Perinatol. 2022 Dec;42(12):1703-1707.

Carpenter R, Srdanovic N, Rychlik K, Sen S, et al. The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia. J Perinatol. 2022;42(6):788- 795.

Sen S, Levy PT, Hamrick SEG, et al. Training pathways and careers for neonatologists interested in cardiovascular care. J Perinatol. 2022;42(4):534-539.

Sen S, Duchon J, Lampl B, Aspelund G, Bacha E, Krishnamurthy G. Heterotaxy syndrome infants are at risk for early shunt failure after Ladd procedure. Ann Thorac Surg. 2015 Mar;99(3):918-25