• Ivan I Kirov MD
• Appointments:
  714-509-8636
• Office: 714-509-4348
• Specialty: Oncology
• Board Certified: Pediatric Hematology/Oncology, Hematology,

Hodgkin’s

Ivan I Kirov MD is on staff at CHOC Hospital in Orange and CHOC Mission Hospital.

Locations

Outpatient Clinic, Hyundai Cancer Institute at CHOC
1201 W. La Veta Avenue
Orange, CA 92868
phone: 714-509-8636
fax: 714-509-4748

Education

• Medical School
  Medical Academy, Sofia, Bulgaria
• Postdoctoral Fellowship
  Pediatric Hematology/Oncology at CHOC Hospital, Orange, CA
• Postdoctoral Fellowship
  Pediatric Hematology/Oncology at the National Institute of Hematology, Medical Academy, Sofia, Bulgaria
• Residency
  Pediatrics Residency at Westchester County Medical Center, New York Medical College, Valhalla, NY
• Visiting Fellowship
  Bone Marrow Transplant Program at Johns Hopkins Hospital Oncology Center, Baltimore, MD

Academic Appointments

• Assistant Clinical Professor
  UC Irvine
• Assistant Professor of Pediatrics
  University of California, Irvine

Administrative Appointments

• Medical Director, Oncology
  CHOC Specialists

Completed Research Support

• Pilot grant for Chao Family Comprehensive Cancer Center seed funding.
  Is loss of SXR expression or function associated with B-cell lymphomas in humans
  Role: Co-Principal Investigator
• Pilot grant for Chao Family Comprehensive Cancer Center seed funding.
  Pilot project to study FGFR3 expression and mutations in pediatric patients.
  Role: Co-Principal Investigator

Honors and Awards

• Physicians of Excellence 2009 – 2015
  Orange County Medical Association

Presentations and Abstracts

Kirov I, Shen V, Sender L, Lones M. Pediatric Diffuse Large Cell Lymphomas in Primary Immunodeficiency have a Non-Germinal Center-B Phenotype.45th Congress of the International Society of Pediatric Oncology, September 2013, Hong Kong. Pediatr Blood Cancer, September 2013, 60, suppl 3:82

Kirov I, Neudorf S, Sender L, Messina J, English M, Crook N. Da-EPOCH-R and EPOCH-R in Treatment of Adolescent Patients with DLBCL. Fourth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, November 2012, New York, NY. British Journal of Hematology, 2012, 159, suppl 1:128

Huynh V, Kirov I, Neudorf S, Zadeh T, Lones M.Post-Transplant Lymphoprolipherative Disorders in Pediatric Bone Marrow Transplanted Recipients Have Non-Germinal Center Phenotype and Unique Ctytogenetic Abnormalities. Fourth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, November 2012, New York, NY. British Journal of Hematology, 2012, 159, suppl 1:107

Fraser C, Brown P, Megason G,, Hyo Seop Ahn, Cho B, Kirov I, Frankel L, Aplenc R, Bensen-Kennedy D, Munteanu M, Weaver J, Harker-Murray P. Open-Label Bendamustine for Pediatric Patients with Relapsed or Refractory Acute Leukemia: Safety and Efficacy Outcomes. In: 53rd ASH Annual Meeting, December 2011, San Diego, California. Blood. 2011 Nov; 118(21): 3602.

Richardson P, Smith A, Grupp S, Kernan N, Arai S, Haut P, Triplett B, Chan KW, Gillio A, Symons H, Adams R, Horn B, Lucas K, Martin PL, Mineishi S, Ball E, Boyer M, Fort J, Kirov I, Lehman L, Madigan C, Massaro J, D’Agostino R, Hannah AL, Tudone E, Hume R, Iacobelli M, Soiffer R, and the Defibrotide Study Group. Defibrotide (DF) in the Treatment of Hepatic Veno-Occlusive Disease (VOD) in Stem Cell Transplant (SCT) and Non- SCT Patients (Pts): Results of a Treatment IND Expanded Access Protocol. In: 53rd ASH Annual Meeting, December 2011, San Diego, California. Blood. 2011 Nov; 118(21): 487.

Professional Organizations

• American Society of Hematology
• Bulgarian Medical Association – Foundation Member
• Bulgarian Society against Leukemia and Tumors in Children – President & Founder

Publications

Abla O, Sandlund JT, Sung L, Brock P, Corbett R, Kirov I, Griffin TC, Blaser S, Weitzman S. A case series of pediatric primary central nervous system lymphoma: favorable outcome without cranial irradiation. Pediatric Blood Cancer. 2006 Dec;47(7):880-5.

Neudorf S, Nourani A, Kempert P, Shen V, Sender L, Kirov I. Chemotherapy and donor leukocyte infusion for relapsed juvenile myelomonocytic leukemia (JMML). Bone Marrow Transplant, 2004; 33: 1069

Lones MA., Kirov I., Said JM., Shinataku IP., Neudorf S. Post-transplant lympho-proliferative disorder after autologous stem cell transplantation in a pediatric patient. Bone Marrow Transplant 2000; Nov; 26 (9): 1021-1024.

Kirov I., and Neudorf S., Biology and clinical utility of hematopoietic stem cells. Pediatric Pathology and Molecular Medicine 2000; 19: 283-302.

Konstantinov D., Bobev D., Michailov G.,   Kirov I. A seven years experience in treatment of childhood leukemia in Bulgaria. Pediatric Hematology Oncol 1998 Mar-April; 15(2): 157-164.