This phase I trial studies the side effects and best dose of prexasertib in treating pediatric patients with solid tumors that have come back after a period of time during which the tumor could not be detected or does not respond to treatment. Checkpoint kinase 1 inhibitor LY2606368 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Principal Investigator:
Josephine HaDuong, MD
Research Coordinator:
Kathryn Duvall
(714) 509-8646
Visit clinicaltrials.gov for more information about this trial.
- IRB Number: 170431
- Sponsor: Children's Oncology Group
- Protocol Number: ADVL1515
- NCT Number: NCT02808650
- Research Type: Adolescents and Young Adults, Brain Tumor/Central Nervous System/Neuro-Oncology, Recurrent/Refractory Cancer, Solid Tumors
- Phase: I
- Status: Active