Free 24/7 Nurse Advice Line: 844-GET-CHOC.

Protecting childhood through leading neurological care.
Our Neuroscience Institute combines specialized skills with the latest technology to treat an array of pediatric brain conditions.

CHOC Neuroscience Institute

As a parent, you are the ultimate protector of your child, and you want the best possible medical care when your child has been diagnosed with a neurological condition. We know that managing your child’s condition can be overwhelming and you might not know where to start.

The CHOC Neuroscience Institute is a dedicated place for kids. Our team of board-certified specialists and neuroscience-trained staff provide a full spectrum of care for disorders of the brain, spine, muscles and central and peripheral nervous systems. We provide coordinated care for a seamless experience, innovative programs and specialized treatments, and pediatric expertise, equipment and facilities.

Find out why Conner’s family turned to the Neuroscience Institute team to get answers—and life-saving care.

Telehealth appointments are available. Please call our Patient Access Center at 888-770-2462 to make an appointment,
or learn more about telehealth here.

A Dedicated Team, Backed by the Latest Technology

Brain conditions in children can be complex and require a team of caregivers, each bringing special expertise. Your child’s care team may include board-certified neurologists and neurosurgeons, nurses and nurse practitioners, social workers, neuropsychologists, rehabilitation therapists, dietitians, psychiatrists, pharmacists, speech and occupational therapists, and child life specialists. The team is backed by the latest technology in brain and spine medicine, including:

  • Top navigation systems for the operating room including FIREFLY and StealthStation S8 with 3D visualization, allowing surgeons to perform safer, more precise procedures
  • Minimally invasive surgery tools including MRI-guided laser ablation and ROSA, a 3D-mapping robotic system that aids surgeons in locating the exact area to operate
  • Video EEG monitoring, wired throughout our hospital, and at-home units that allow children to play and move about normally while undergoing detailed monitoring of the brain
  • ReFlow shunt technology to reverse life-threatening shunt occlusion in patients with hydrocephalus
  • Vagus nerve stimulation (VNS), a “pacemaker for the brain” for reducing seizures, and deep brain stimulation (DBS) for intractable partial seizures and dystonia
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Patient Stories

Smiling Rylee holding three months seizure free sign
Despite her happy disposition, Rylee had a big roadblock: frequent seizures. Six months past her epilepsy surgery, she hasn’t had a single seizure.

Maddy with pediatric neurosurgeon, Dr. William Loudon
At just 6 years old, Madison Morrison has earned the nickname “Miracle Maddy” after recovering from life-saving surgery at CHOC.

Smiling Michelle in bed with stuft toy
Before she was born, Michelle was diagnosed with microcephaly and encephalocele. Today, she’s thriving.

Team Miranda in the CHOC Walk at the Park in 2017
Inspired by her experiences at CHOC, this former patient is planning to major in psychiatry and dreams of becoming a pediatric optometrist.

Why Choose CHOC?

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The CHOC Neuroscience Institute is ranked among the Best Children’s Hospitals by U.S. News & World Report for neurology and neurosurgery.


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We offer the only pediatric neuroscience hospital unit in the region, including dedicated beds for seizure monitoring.


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We have the only Level 4 epilepsy center in Orange County, certified by the National Association of Epilepsy Centers (NAEC).


US News and World Report Best Childrens Hospitals CHOC Neurology-Neurosurgery
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We are forever grateful and feel blessed for this wonderful hospital for keeping our family whole.

Contact the Neuroscience Institute

Call us today at 714-509-4765 for appointments with a neurologist or neurosurgeon, scheduling a neurodiagnostic test, physician referrals and general questions about our programs and services. Our locations include:


Joe C. Wen & Family Center for Advanced Care, UCI Health - Irvine
CHOC Center for Children’s Health

Building: Joe C. Wen & Family Center for Advanced Care, UCI Health - Irvine | 19200 Jamboree Road, Suite 2000 | Irvine, CA 92612

Autism Center Lobby
CHOC Neuroscience Institute Outpatient Center – Newly Expanded

Building: CHOC Commerce Tower | 505 S. Main St., Suite 350 | Orange, CA 92868 | 888-770-2462

Map showing location of CHOC Children’s Health Center at PIH Health
CHOC Health Center at PIH Health

15725 E Whittier Blvd, #300 | Whittier, CA 90603 | Appointments: 888-770-2462

Map showing location of CHOC Children's Health Center Mission Viejo
CHOC Health Center, Mission Viejo

26691 Plaza, Suite 130 | Mission Viejo, CA 92691

Map showing location of CHOC Children's Health Center Corona
CHOC Health Center, Corona

854 Magnolia Ave - #101 | Corona, CA 92879 | 888-770-2462

Map showing location of CHOC Children’s Specialty Center, Newport Beach
CHOC Specialty Center, Newport Beach

500 Superior Avenue - Suite 140 | Newport Beach, CA 92663

Minimally Invasive Neurosurgery

At CHOC, our board-certified neurosurgeons bring the highest levels of expertise and experience to even the most complex disorders of the brain, spine and central and peripheral nervous systems. Our techniques used in minimally invasive surgery improves accuracy and significantly reduces surgery/anesthesia time, so childhood doesn’t have to be put on pause.


Laser interstitial thermal therapy (LITT), or laser ablation, is among the latest advancements in minimally invasive neurosurgery, allowing surgeons to reach difficult areas of the brain