Free 24/7 Nurse Advice Line: 844-GET-CHOC.

Aaron F. Sassoon, MD, PhD - Surgical & Hematopathology

Aaron F. Sassoon, MD, PhD - Surgical & Hematopathology

  • Aaron F Sassoon MD
  • Appointments:
  • Specialty: Pathology
  • Board Certified: Anatomic Pathology, Clinical Pathology, Hematopathology

Recognized for his leadership and expertise, Dr. Aaron Sassoon serves as Medical Director of CHOC Pathology Department. He is board certified in Hematology, Anatomic and Clinical Pathology. He received his PhD in Cellular Biology and his medical degree from the University of Southern California (USC). He completed his Anatomic Pathology & Clinical Pathology residency at the University of California, Los Angeles (UCLA). He finalized his Hematopathology fellowship training at world-renowned Cedars-Sinai Medical Center in Los Angeles, California. He has over 30 years of experience where his philosophy has been put into practice.

Aaron F Sassoon MD is on staff at CHOC Hospital in Orange .


CHOC Pathology
1201 W. La Veta Ave
Orange, CA 92868
phone: 714-509-9012
fax: 714-509-9027

Orange County Pathology Medical Group
805 W. La Veta Ave, #104
Orange, CA 92868
phone: 714-288-4044
fax: 714-288-4042


  • Undergrad
    Bachelor of Science, Biochemistry
    University of California Los Angeles (UCLA), Los Angeles, CA
  • Medical School
    Doctor of Medicine
    University of Southern California (USC) School of Medicine, Los Angeles, CA
    Doctor of Philosophy in Cellular Biology
    University of Southern California (USC), Los Angeles, CA
  • Residency
    Anatomic Pathology & Clinical Pathology
    University of California Los Angeles (UCLA) Medical Center, Los Angeles, CA
  • Fellowship
    Cedars-Sinai Medical Center, Los Angeles, CA

Special Interests

  • Lymphoma
  • Gastrointestinal Pathology
  • Genitourinary Pathology
  • Pediatric Pathology

Administrative Appointments

  • Medical Director
    Department of Pathology, CHOC
  • President
    Orange County Pathology Medical Group (OCPMG)


  • College of American Pathologists (CAP)
  • American Society of Clinical Pathology (ASCP)
  • California Society of Pathologist (CSP)


Said JW, Nash G, Banks-Schlegel S, Sassoon AF, Murakami S, Shintaku IP. Keratin in human lung tumors. Patterns of localization of different-molecular-weight keratin proteins. Am J Pathol. 1983 Oct;113(1):27-32. PMID: 6194690. PMCID: PMC1916295.

Said JW, Nash G, Sassoon AF, Shintaku IP, Banks-Schlegel S. Involucrin in lung tumors. A specific marker for squamous differentiation. Lab Invest. 1983 Nov;49(5):563-8. PMID: 6195449.

Said JW, Shintaku IP, Chien K, Sassoon AF. Peripheral T cell lymphoma (immunoblastic sarcoma of T cell type): An immuno-ultrastructural study. Hum Pathol. 1984 Apr;15(4):324-9. PMID: 6609115.

Said JW, Nash G, Banks-Schlegel S, Sassoon AF, Shintaku IP. Localized fibrous mesothelioma: An immunohistochemical and electron microscopic study. Hum Pathol. 1984 May;15(5):440-3. PMID: 6202620.

Walts AE, Said JW, Shintaku IP, Sassoon AF, Banks-Schlegel S. Keratins of different molecular weight in exfoliated mesothelial and adenocarcinoma cells — an aid to cell identification. Am J Clin Pathol. 1984 Apr;81(4):442-6. PMID: 6199968.

Said JW, Sassoon AF, Shintaku IP, Banks-Schlegel S. Involucrin in squamous and basal cell carcinomas of the skin: An immunohistochemical study. J Invest Dermatol. 1984 May;82(5):449-52. PMID: 6210326.

Said JW, Shintaku IP, Teitelbaum A, Chien K, Sassoon AF. Distribution of T-cell phenotypic subsets and surface immunoglobulin-bearing lymphocytes in lymph nodes from male homosexuals with persistent generalized adenopathy: An immunohistochemical and ultrastructural study. Hum Pathol. 1984 Aug;15(8):785- 90. PMID: 6235166.

Said JW, Vimadalal S, Nash G, Shintaku IP, Heusser RC, Sassoon AF, Lloyd RV. Immunoreactive neuron-specific enolase, bombesin, and chromogranin as markers for neuroendocrine lung tumors. Hum Pathol. 1985 Mar;16(3):236-40. PMID: 3972403.

Sassoon AF, Said JW, Nash G, Shintaku IP, Banks-Schlegel S. Involucrin in intraepithelial and invasive squamous cell carcinomas of the cervix: An immunohistochemical study. Hum Pathol. 1985 May;16(5):467-70. PMID: 3886522.

Said JW, Sassoon AF, Shintaku IP, Chien K, Pinkus GS. Immuno-ultrastructural localization of B-cell-specific monoclonal antibodies B1 and B2. J Histochem Cytochem. 1986 May;34(5):607-11. PMID: 3517145.

Said JW, Sassoon AF, Chien K, Shintaku IP, Pinkus GS. Immunoultrastructural and morphometric analysis of B lymphocytes in human germinal centers. Evidence for alternate pathways of follicular transformation. Am J Pathol. 1986 May;123(2):390-7. PMID: 2422945. PMCID: PMC1888308.

Said JW, Sassoon AF, Shintaku IP, Corcoran P, Nichols SW. Polymerase chain reaction for bcl-2 in diagnostic lymph node biopsies. Mod Pathol. 1990 Nov;3(6):659-63. PMID: 2263590.

Said JW, Sassoon AF, Shintaku IP, Kurtin PJ, Pinkus GS. Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin’s disease. Results of Southern blot analysis and polymerase chain reaction. Am J Pathol. 1991 Feb;138(2):261-4. PMID: 1899539. PMCID: PMC1886181.

Elami A, Laks H, Milgalter E, Sassoon AF. Use of Dacron mesh coated pericardium for aortic augmentation. J Card Surg. 1993 Jul;8(4):488-91. PMID: 8353337.

Ward WG, Mikaelian K, Dorey F, Mirra JM, Sassoon A, Holmes EC, Eilber FR, Eckardt JJ. Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases. J Clin Oncol. 1994 Sep;12(9):1849-58. PMID: 8083708.

Yao K, Singer FR, Roth SI, Sassoon A, Ye C, Giuliano AE. Weight of normal parathyroid glands in patients with parathyroid adenomas. J Clin Endocrinol Metab. 2004 Jul;89(4):3208-13. PMID: 15240594.

Buchbinder D, Younes B, Sassoon A, Soni A, Hsieh L, Puthenveetil G, Stites J, Ness- Jorden T, Neudorf S, Nugent D. Inflammatory polyps following successful HLA- matched cord blood transplantation in a patient with X-linked lymphoproliferative syndrome. Pediatr Transplant. 2012 Aug;16(5):E188-91. PMID: 21736679.

Micha JP, Sassoon AF, Wong H, Goldstein BH. Prolonged remission of recurrent cervical carcinoma following paclitaxel and carboplatin chemotherapy with paclitaxel maintenance chemotherapy. Anticancer Drugs. 2015 Aug;26(7)793-6. PMID: 25933247.

McEachron TA, Kirov I, Wungwattana M, Cortes D, Zabokrtsky KB, Sassoon A, Craig D, Carpten JD, Sender LS. Successful treatment of genetically profiled pediatric extranodal NK/T-cell lymphoma targeting oncogenic STAT3 mutation. Pediatr Blood Cancer. 2016 Apr;63(4):727-30. PMID: 26727971.

Buchbinder D, Sassoon A. You GATA look at the marrow! Blood. 2016 Jul 28;128(4):603. PMID: 28092903.

Buchbinder D, Sassoon A. A case of bad Carma! Blood. 17 Mar 23;129(12):1737. PMID: 28336733.

Bhangoo A, Wang P, Young I, Sassoon A, Taguibao R, Khoury A. A severe case of testotoxicosis in an infant due to a c.1732G>C (p.ASP578His) LHCGR gene mutation associated with nodular Leydig cell hyperplasia. International Journal of Medical

Reviews and Case Reports. 2018. DOI: 10.5455/IJMRCR.Leydig-cell-hyperplasia-mutation.

Buchbinder DK, Sassoon A, Sy A. Neonatal hyperbilirubinemia: Diagnostic clues from the peripheral blood smear. J Pediatr Hematol Oncol. 2020 Oct;42(7):448. PMID: 32590416.

Buchbinder DK, Singh J, Dao T, Sassoon A, Arrieta A. Case report: Pseudomonas can take a toll on a patient. F1000Res. 2021 Jul 1;10:526. PMID: 34381593.

Lee W, HaDuong J, Sassoon A, Dao T, Nael A. A liver transplant for local control in a pediatric patient with metastatic TFE3-associated perivascular epithelioid cell tumor (PEComa) to the liver. Case Rep Pathol. 2021 Oct 5;2021:3924565. PMID: 34650822. PMCID: PMC8510831.

Yu J, Sassoon AF, Gholizadeh M, Guner YS, Awan S. Rhabdomyosarcoma of the gallbladder. J Pediatr Surg Case Rep. Available online 26 April 2022.


2013-2023: Southern California Super Doctors